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TCR/BCR Repertoire Analysis
Neoepitope Analysis

By conducting RNA seq and Exose seq together, specific gene mutations which are specific to individual cancers can be identified. In addition, by taking into account intermolecular coupling, variant peptides (neoepitope) capable of presenting an antigen will be identified. This identification can also be used for indel, long indel, and splicing variants using sequence data.
16S rRNA Bacterial Flora Analysis

Distribution of bacterial species (bacterial flora) in samples can be analyzed by examining the V1V2 or V3V4 region of the 16S rRNA gene preserved in each bacterial species using next generation sequencing. This analysis can be applied not only to biologically derived samples (feces, saliva, etc.), but also to environmentally derived samples (soil, food, etc.).
Publications
- 2022/05/23
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Clinical immunity
Dr. Masayo Ukita in the Department of Gynecology and Obstetrics, Kyoto University Graduate School of Medicine has published a paper in "JCI Insight" titled "CXCL13-producing CD4+ T cells accumulate in early phase of tertiary lymphoid structures in ovarian cancer".
- 2022/05/13
- Paper
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Dr. Koichiro Yoshimaru in the Department of Pediatric Surgery, Kyushu University Graduate School of Medical Sciences has published a paper in "Scientific Reports" titled "Dental pulp stem cells as a therapy for congenital entero-neuropathy".
- 2022/04/26
- Paper
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Basal immunity
Dr. Yasuhiro Kazuki in the Chromosome Engineering Research Center, Tottori University has published in "Nature Communications" titled "Efficient human-like antibody repertoire and hybridoma production in trans-chromosomic mice carrying megabase-sized human immunoglobulin loci".
TCR/BCR Repertoire analysis Guidebook
MUST READ! For users considering Repertoire analysis
An easy-to-understand repertoire analysis guidebook has been prepared which explains in plain language for the questions such as what is immune repertoire analysis and what kind of preparation is necessary.
Please request the guidebook from below if desired.
