A paper utilizing our TCR repertoire analysis was published by Dr. Tatsuya Suwabe et al., Department of Hematopoietic Stem Cell Transplantation, Niigata University Medical and Dental Hospital.
In this paper, they investigated how long and to what extent WT1-specific CD8+ cytotoxic T cells (CTL) persisted after WT1 peptide vaccination, and reported that the immune response persisted for more than 10 years even after vaccination was discontinued.
Our TCR repertoire analysis was performed using WT1-specific CTLs after mixed lymphocyte peptide culture and revealed the diversity of WT1-specific CTLs 11 years after vaccination.

Int J Hematol.
Decade-long WT1-specific CTLs induced by WT1 peptide vaccination

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